Various of the disclosed embodiments provide systems and methods for enabling LTE® and wireless, e.g., ISM band, applications to coexist on a same device or on separate devices in proximity to one another. Some embodiments implement a remediation and/or channel transition process for the wireless devices following detection of LTE®-related interference. During remediation, the device may, e.g., adjust the wireless power levels, EDCA backoff times, signal thresholds, etc. In some embodiments, if the remediation actions prove ineffective, the wireless peers may be relocated to a channel further from the interfering LTE® band. The determination to remediate or reallocate may be based on various contextual factors, e.g., the character of the peer devices and the applications being run.