Invention Grant
- Patent Title: Cyclic compounds
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Application No.: US15356906Application Date: 2016-11-21
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Publication No.: US09828357B2Publication Date: 2017-11-28
- Inventor: Toshitake Kobayashi , Morihisa Saitoh , Yasufumi Wada , Hiroshi Nara , Nobuyuki Negoro , Taisuke Katoh , Masashi Yamasaki , Takahiro Tanaka , Naomi Kitamoto
- Applicant: Takeda Pharmaceutical Company Limited
- Applicant Address: JP Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agency: Foley & Lardner LLP
- Priority: JP2015-095817 20150508
- Main IPC: C07D317/72
- IPC: C07D317/72 ; C07C317/12 ; C07D309/28 ; C07C317/44 ; C07C317/46

Abstract:
The present invention provides compounds having a Toll-like receptor 4 (TLR4) signaling inhibitory action useful as preventive and therapeutic drugs of inflammatory disease and/or central nervous system disease or diseases such as chemotherapy-induced peripheral neuropathy (CIPN), chemotherapy-induced neuropathic pain (CINP), liver injury, ischemia-reperfusion injury (IRI) and the like. The present invention relates to a compound represented by formula (I) and a salt thereof: wherein, each symbol is explained in greater detail in the specification.
Public/Granted literature
- US20170066737A1 CYCLIC COMPOUNDS Public/Granted day:2017-03-09
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