Invention Grant
- Patent Title: Substituted pyrazolopyrimidines and method of use
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Application No.: US15133851Application Date: 2016-04-20
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Publication No.: US09828381B2Publication Date: 2017-11-28
- Inventor: Ramin Faghih , Achim Moeller , Michael Ochse , Frauke Pohlki , Martin Schmidt , Kevin Sippy , Sean Turner , Elizabeth Louise Van Der Kam
- Applicant: AbbVie Deutschland GmbH & Co. KG , AbbVie Inc.
- Applicant Address: DE Wiesbaden US IL North Chicago
- Assignee: AbbVie Deutschland GmbH & Co. KG,AbbVie Inc.
- Current Assignee: AbbVie Deutschland GmbH & Co. KG,AbbVie Inc.
- Current Assignee Address: DE Wiesbaden US IL North Chicago
- Agency: Neal, Gerber & Eisenberg LLP
- Priority: WOPCT/CN2015/076978 20150420; EP15168924 20150522
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D519/00

Abstract:
Compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, L1 and G1 are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by positive allosteric modulation of the γ-aminobutyric acid B (GABA-B) receptor. Methods for making the compounds are described. Also described are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.
Public/Granted literature
- US20160304527A1 SUBSTITUTED PYRAZOLOPYRIMIDINES AND METHOD OF USE Public/Granted day:2016-10-20
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