- 专利标题: Method for producing composition for external use containing physiologically acceptable salt of tranexamate
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申请号: US13814549申请日: 2011-07-15
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公开(公告)号: US09833401B2公开(公告)日: 2017-12-05
- 发明人: Masayoshi Miyamoto , Tomomi Kuromiya , Daisuke Suzuki
- 申请人: Masayoshi Miyamoto , Tomomi Kuromiya , Daisuke Suzuki
- 申请人地址: FR Neuilly sur Seine
- 专利权人: CHANEL PARFUMS BEAUTE
- 当前专利权人: CHANEL PARFUMS BEAUTE
- 当前专利权人地址: FR Neuilly sur Seine
- 代理机构: Young & Thompson
- 优先权: JP2010-177580 20100806
- 国际申请: PCT/IB2011/001865 WO 20110715
- 国际公布: WO2012/017313 WO 20120209
- 主分类号: A61K8/81
- IPC分类号: A61K8/81 ; A61K8/41 ; A61K8/73 ; A61Q19/02 ; A61K8/00 ; A61K8/84 ; A61K8/02
摘要:
A composition for external use containing a tranexamate as an active ingredient with suppressed sticky or oily feeling but having a fresh feel of use, and a method for producing the same. A tranexamate salt can be dispersed stably in an aqueous medium by (a) dissolving the tranexamate salt and an amphiphilic polymer in water, a water-soluble organic solvent or a mixture thereof; and (b) adding a mixed solution obtained in the step (a) to an aqueous medium, and thus keeping the tranexamate salt in molecular assembly particles formed of the amphiphilic polymer.
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