The present invention is to provide a thermal transfer sheet which is able to prevent a heat resistant slipping layer from transferring to a guide roller, etc., and which is able to prevent wrinkles when printing. Disclosed is a thermal transfer sheet including a substrate sheet, a thermal transfer layer disposed on one side of the substrate sheet, and a heat resistant slipping layer disposed on the other side of the substrate sheet via a primer layer, wherein the primer layer contains a cured product of a resin composition containing one or more kinds of resins selected from a urethane resin and a polyester resin and a compound having a functional group selected from an epoxy group, a silanol group and a hydrolyzable silyl group.