A system according to the principles of the present disclosure includes a model predictive control (MPC) module and an actuator module. The MPC module generates a set of possible target values for an actuator of an engine and predicts an operating parameter of the engine for each of the possible target values. The MPC module determines a weighting value associated with each of the target values based on a corresponding iteration number and determines a cost for the set of possible target values based on the predicted operating parameters and the weighting values. The MPC module selects the set of possible target values from multiple sets of possible target values based on the cost and sets target values to the possible target values of the selected set. The actuator module controls an actuator of an engine based on at least one of the target values.