An array substrate is described. The array substrate with a polarity inversion of drive voltage signal in a plurality of data lines comprises a plurality of gate line sets being sequentially arranged, wherein each gate line set comprises two gate lines having an odd gate line and an even gate line respectively; a plurality of data line sets being sequentially arranged and vertically interlaced with the gate line sets, wherein each data line set comprises two data lines having an odd data line and an even data line respectively; wherein a plurality of sub-pixels are sequentially disposed between two adjacent gate line sets, connection positions of a portion of sub-pixels to the odd gate line and the even gate line in one gate line set respectively are changed in a predetermined amount of data line spaced apart.