- 专利标题: Microarray device for screening or locating HSP90 inhibitors or inhibitors of further disease-relevant target structures
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申请号: US14128298申请日: 2012-04-20
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公开(公告)号: US09891230B2公开(公告)日: 2018-02-13
- 发明人: Dieter Melzner , Thomas Scheper , Thomas Schueler , Frank Stahl , Denise Van Rossum , Johanna-Gabriela Walter , Carsten Zeilinger
- 申请人: Dieter Melzner , Thomas Scheper , Thomas Schueler , Frank Stahl , Denise Van Rossum , Johanna-Gabriela Walter , Carsten Zeilinger
- 申请人地址: DE
- 专利权人: SARTORIUS STEDIM BIOTECH GMBH
- 当前专利权人: SARTORIUS STEDIM BIOTECH GMBH
- 当前专利权人地址: DE
- 代理机构: McDonald Hopkins LLC
- 优先权: DE102011106984 20110708
- 国际申请: PCT/EP2012/001725 WO 20120420
- 国际公布: WO2013/007324 WO 20130117
- 主分类号: G01N33/543
- IPC分类号: G01N33/543 ; G01N33/68
摘要:
The present invention relates to a microarray device for the screening or the finding of protein inhibitors, to a method for the production thereof, and to a corresponding method for screening or finding protein inhibitors. The microarray device according to the invention comprises a solid supporting element having a support material, at least one protein immobilized thereon for which inhibitors are to be screened or found, and at least one known inhibitor of the at least one protein, the inhibitor being bound to the at least one protein and comprising a detectable label.