Invention Grant
- Patent Title: Methods of treating cancer using PD-L1 axis binding antagonists and VEGF antagonists
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Application No.: US14556774Application Date: 2014-12-01
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Publication No.: US09895441B2Publication Date: 2018-02-20
- Inventor: Heather Maecker , Bryan Irving
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: GENENTECH, INC.
- Current Assignee: GENENTECH, INC.
- Current Assignee Address: US CA South San Francisco
- Agency: Morrison & Foerster LLP
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K31/282 ; A61K31/519 ; A61K31/513 ; C07K16/22 ; C07K16/28 ; A61K39/00
Abstract:
The present invention describes combination treatment comprising a PD-1 axis binding antagonist, chemotherapy and optionally a VEGF antagonist and methods for use thereof, including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer.
Public/Granted literature
- US20150320859A1 METHODS OF TREATING CANCER USING PD-L1 AXIS BINDING ANTAGONISTS AND VEGF ANTAGONISTS Public/Granted day:2015-11-12
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