Site-specific delivery of nucleic acids by combining targeting ligands with endosomolytic components

Invention Grant

US09895448B2 Site-specific delivery of nucleic acids by combining targeting ligands with endosomolytic components 有权

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Patent Title: Site-specific delivery of nucleic acids by combining targeting ligands with endosomolytic components
Application No.: US15133010

Application Date: 2016-04-19
Publication No.: US09895448B2

Publication Date: 2018-02-20
Inventor: Muthiah Manoharan , Kallanthottathil G. Rajeev , David Butler , Muthusamy Jayaraman
Applicant: Arbutus Biopharma Corporation
Applicant Address: CA Burnaby, BC
Assignee: Arbutus Biopharma Corporation
Current Assignee: Arbutus Biopharma Corporation
Current Assignee Address: CA Burnaby, BC
Agency: Viksnins Harris Padys Malen LLP
Main IPC: A61K47/48
IPC: A61K47/48 ; C12N15/113 ; A61K48/00 ; C12N15/11 ; C12N15/87 ; A61K47/54 ; A61K47/55

Site-specific delivery of nucleic acids by combining targeting ligands with endosomolytic components

Abstract:

The invention relates to compositions and methods for site-specific delivery of nucleic acids by combining them with targeting ligands and endosomolytic components.

Public/Granted literature

US20160367687A1 SITE-SPECIFIC DELIVERY OF NUCLEIC ACIDS BY COMBINING TARGETING LIGANDS WITH ENDOSOMOLYTIC COMPONENTS Public/Granted day:2016-12-22

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