Technologies for native code invocation using binary analysis are described. A computing device for invoking native code from managed code using binary analysis receives a call from a thread executing a managed code segment to execute a native code segment. The computing device performs a binary analysis of the native code segment and generates, from the binary analysis, a complexity indicator that indicates a level of complexity of the native code segment by comparing the native code segment to at least one predefined complexity rule. Additionally, the computing device stores a status of the thread based on the complexity indicator and executes the native code segment. Other embodiments are described and claimed.