A method of processing a reception signal and a MIMO receiver are disclosed. The method includes the steps of selecting a reference RE from an RE group including a plurality of REs, generating a preprocessing filter to be shared by the plurality of the REs belonging to the RE group based on channel information of the reference RE and generating detection signals for the plurality of the REs in a manner of compensating reception signals for each of the plurality of the REs using the preprocessing filter and channel information of each of the plurality of the REs.