Invention Grant
- Patent Title: Tricyclic pyrido-carboxamide derivatives as rock inhibitors
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Application No.: US14900238Application Date: 2014-07-01
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Publication No.: US09914740B2Publication Date: 2018-03-13
- Inventor: Mimi L. Quan , Zilun Hu , Cailan Wang , Sharanabasappa Patil
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Hong Liu
- International Application: PCT/US2014/044988 WO 20140701
- International Announcement: WO2015/002915 WO 20150108
- Main IPC: C07D491/052
- IPC: C07D491/052 ; C07D519/00 ; C07D471/04 ; C07D491/048 ; C07D498/04

Abstract:
The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.
Public/Granted literature
- US20160152628A1 TRICYCLIC PYRIDO-CARBOXAMIDE DERIVATIVES AS ROCK INHIBITORS Public/Granted day:2016-06-02
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