Invention Grant
- Patent Title: Antibodies targeting CDH19 for melanoma
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Application No.: US14762053Application Date: 2014-01-27
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Publication No.: US09920121B2Publication Date: 2018-03-20
- Inventor: Shouhua Xiao , Zheng Pan , Dineli Wickramasinghe , M. Shawn Jeffries , Chadwick Terence King , Brian Mingtung Chan
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- Agency: Marshall, Gerstein & Borun LLP
- International Application: PCT/EP2014/051551 WO 20140127
- International Announcement: WO2014/114801 WO 20140731
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; C07K16/30 ; A61K47/68 ; A61K39/00

Abstract:
The present disclosure provides a human antibody or antigen binding fragment thereof or an antibody construct comprising a human binding domain or antigen binding fragment thereof capable of binding to human CDH19 on the surface of a target cell. The disclosure relates to a nucleic acid sequence encoding the antibody or antigen binding fragment thereof contained in the antibody construct, a vector comprising the nucleic acid sequence and a host cell transformed or transfected with the vector. Furthermore, the disclosure relates to a process for the production of the antibody construct of the disclosure, a medical use or a method of treatment using the antibody construct and a kit comprising the antibody or antigen binding fragment thereof or the antibody construct.
Public/Granted literature
- US20150322151A1 ANTIBODIES TARGETING CDH19 FOR MELANOMA Public/Granted day:2015-11-12
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