- Patent Title: Use of gastrointestinally administered porous enteron sorbent polymers to prevent or treat radiation induced mucositis, esophagitis, enteritis, colitis, and gastrointestinal acute radiation syndrome
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Application No.: US15515328Application Date: 2015-10-02
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Publication No.: US09931357B2Publication Date: 2018-04-03
- Inventor: Humayra Begum Ali , Thomas D. Golobish , Vincent J. Capponi , Phillip P. Chan , Wei-Tai Young , Andrew Robert Scheirer
- Applicant: CYTOSORBENTS CORPORATION
- Applicant Address: US NJ Monmouth Junction
- Assignee: CytoSorbents Corporation
- Current Assignee: CytoSorbents Corporation
- Current Assignee Address: US NJ Monmouth Junction
- Agency: Baker & Hostetler LLP
- International Application: PCT/US2015/053622 WO 20151002
- International Announcement: WO2016/054458 WO 20160407
- Main IPC: A61M31/00
- IPC: A61M31/00 ; A61K31/74 ; A61K31/765 ; A61K9/00

Abstract:
Disclosed herein are compositions and methods for preventing or treating acute or chronic oral mucositis, esophagitis, enteritis, colitis, or gastrointestinal acute radiation syndrome (GI-ARS) caused by radiation exposure, using one or more enteron sorbent polymers administered gastrointestinally (e.g. orally, via feeding or gastric tube, via ostomy, or rectally).
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