A portable gas cylinder is disclosed which includes a gas cylinder including an upper portion having a valve port and an annular mounting collar surrounding the valve port, a handle assembly including a housing having a body portion configured to mate with the upper portion of the gas cylinder, a pair of diametrically opposed gripping handles extending upwardly from the body portion and a central aperture providing access to the valve port, wherein an annular retention channel is formed in an undersurface of the housing, extending about the periphery of the central aperture for receiving the mounting flange of the gas cylinder, and a blocking ring for securing the mounting flange of the gas cylinder within the retention channel of the handle assembly.