Invention Grant
- Patent Title: FXR (NR1H4) modulating compounds
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Application No.: US14971825Application Date: 2015-12-16
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Publication No.: US09938278B2Publication Date: 2018-04-10
- Inventor: Christian Gege , Claus Kremoser , Olaf Kinzel , Peter A. Blomgren , Kevin S. Currie , Jeffrey E. Kropf , Aaron C. Schmitt , William J. Watkins , Jianjun Xu
- Applicant: Gilead Sciences, Inc.
- Applicant Address: US CA Foster City
- Assignee: GILEAD SCIENCES, INC.
- Current Assignee: GILEAD SCIENCES, INC.
- Current Assignee Address: US CA Foster City
- Priority: EP14004260 20141217
- Main IPC: A61K31/506
- IPC: A61K31/506 ; C07D471/08 ; C07D401/14 ; C07D413/14 ; C07D261/08 ; C07D413/12 ; C07D417/14
Abstract:
The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.
Public/Granted literature
- US20170298068A1 NOVEL FXR (NR1H4) MODULATING COMPOUNDS Public/Granted day:2017-10-19
Information query
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