- 专利标题: Therapeutic pyrazolyl thienopyridines
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申请号: US14995556申请日: 2016-01-14
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公开(公告)号: US09938289B2公开(公告)日: 2018-04-10
- 发明人: Stephen D. Barrett , James B. Kramer , Mark L. Boys , Huifen Chen
- 申请人: THESAN PHARMACEUTICALS, INC.
- 申请人地址: US CA Rancho Santa Fe
- 专利权人: FBM THERAPEUTICS, LLC
- 当前专利权人: FBM THERAPEUTICS, LLC
- 当前专利权人地址: US CA Rancho Santa Fe
- 代理机构: Cooper & Dunham LLP
- 代理商 John P. White
- 主分类号: C07D495/04
- IPC分类号: C07D495/04 ; A61K9/14 ; A61K31/4365 ; A61K9/00
摘要:
The present invention provides for compounds of Formula I, and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, and R7 have any of the values defined therefor in the specification, and pharmaceutically acceptable salts thereof, that are useful as therapeutic agents in the treatment of TGFβ-mediated conditions, including cancer and fibrotic disorders. Also provided are pharmaceutical compositions comprising one or more compounds of Formula I.
公开/授权文献
- US20160200735A1 THERAPEUTIC PYRAZOLYL THIENOPYRIDINES 公开/授权日:2016-07-14