Invention Grant
- Patent Title: Pluripotent stem cell expansion and passage using a rocking platform bioreactor
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Application No.: US14956408Application Date: 2015-12-02
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Publication No.: US09944894B2Publication Date: 2018-04-17
- Inventor: Brian Michael Davis , Kenneth Roger Conway , Evelina Roxana Loghin , Xiaohua Zhang
- Applicant: General Electric Company
- Applicant Address: US NY Schenectady
- Assignee: GENERAL ELECTRIC COMPANY
- Current Assignee: GENERAL ELECTRIC COMPANY
- Current Assignee Address: US NY Schenectady
- Agent Pabitra K. Chakrabarti
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12M1/00 ; C12M3/06 ; C12M1/26 ; C12M1/33 ; C12M1/36 ; C12N5/0735 ; C12N5/074
Abstract:
Provided herein are novel methods for expansion and passaging of cell aggregates comprising stem cells and/or differentiated cells and comprising the use of closed systems on rocking platform bioreactors. The methods of the invention permit closed system serial passage expansion of pluripotent stem cells and/or progeny thereof with associated pluripotency markers and differentiation potential.
Public/Granted literature
- US20160340633A1 PLURIPOTENT STEM CELL EXPANSION AND PASSAGE USING A ROCKING PLATFORM BIOREACTOR Public/Granted day:2016-11-24
Information query
