Invention Grant
- Patent Title: Bacillus based delivery system and methods of use
-
Application No.: US14849123Application Date: 2015-09-09
-
Publication No.: US09956277B2Publication Date: 2018-05-01
- Inventor: George C. Stewart , Brian Matthew Thompson
- Applicant: The Curators of the University of Missouri
- Applicant Address: US MO Columbia
- Assignee: The Curators of the University of Missouri
- Current Assignee: The Curators of the University of Missouri
- Current Assignee Address: US MO Columbia
- Agency: Senniger Powers LLP
- Main IPC: A61K39/07
- IPC: A61K39/07 ; C12N15/75 ; C12N3/00 ; A61K39/00 ; A61K39/12 ; C07K14/32 ; C12N11/16 ; A61K35/00

Abstract:
Herein a Bacillus exosporium antigen delivery (BEAD) system that provides a means to introduce recombinant proteins or small molecules into the exosporium of members of the B. cereus family of bacteria, i.e. B. anthracis, B. cereus, and B. thuringiensis, is disclosed. The system results in the surface display of recombinant proteins or small molecules such that they can stimulate an immune response. In addition, methods of making and using the system are described.
Public/Granted literature
- US20160051656A1 BACILLUS BASED DELIVERY SYSTEM AND METHODS OF USE Public/Granted day:2016-02-25
Information query