Invention Grant
- Patent Title: Conjugates of RGD peptides and porphyrin or (bacterio)chlorophyll photosynthesizers and their uses
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Application No.: US13447825Application Date: 2012-04-16
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Publication No.: US09957293B2Publication Date: 2018-05-01
- Inventor: Avigdor Scherz , Yoram Salomon , Efrat Rubinstein , Alexander Brandis , Doron Eren , Karin Neimann
- Applicant: Avigdor Scherz , Yoram Salomon , Efrat Rubinstein , Alexander Brandis , Doron Eren , Karin Neimann
- Applicant Address: IL Rehovot
- Assignee: YEDA RESEARCH AND DEVELOPMENT COMPANY LTD.
- Current Assignee: YEDA RESEARCH AND DEVELOPMENT COMPANY LTD.
- Current Assignee Address: IL Rehovot
- Agency: Browdy and Neimark, PLLC
- Main IPC: C07K5/12
- IPC: C07K5/12 ; C07K5/09 ; C07K5/10 ; C07K7/06 ; C07K7/64 ; A61K41/00 ; A61K51/08 ; G01N33/574 ; A61K47/64 ; A61K51/00 ; A61M36/14
Abstract:
Conjugates of porphyrin, chlorophyll and bacteriochlorophyll photosensitizers with RGD-containing peptides or RGD peptidomimetics are provided that are useful for photodynamic therapy (PDT), particularly vascular-targeted PDT (VTP), of tumors and nonneoplastic vascular diseases such as age-related macular degeneration, and for diagnosis of tumors by different techniques.
Public/Granted literature
- US20120294801A1 CONJUGATES OF RGD PEPTIDES AND PORPHYRIN OR (BACTERIO)CHLOROPHYLL PHOTOSYNTHESIZERS AND THEIR USES Public/Granted day:2012-11-22
Information query
