Invention Grant
- Patent Title: Composition for preventing or treating neurodegenerative diseases, containing Ramalin
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Application No.: US15520100Application Date: 2014-10-24
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Publication No.: US09968576B2Publication Date: 2018-05-15
- Inventor: Joung Han Yim , Il-Chan Kim , Se Jong Han , Dong-Gyu Jo
- Applicant: KOREA INSTITUTE OF OCEAN SCIENCE AND TECHNOLOGY
- Applicant Address: KR Gyeonggi-Do
- Assignee: KOREA INSTITUTE OF OCEAN SCIENCE AND TECHNOLOGY
- Current Assignee: KOREA INSTITUTE OF OCEAN SCIENCE AND TECHNOLOGY
- Current Assignee Address: KR Gyeonggi-Do
- Agency: Hultquist, PLLC
- Agent Steven J. Hultquist
- International Application: PCT/KR2014/010057 WO 20141024
- International Announcement: WO2016/064009 WO 20160428
- Main IPC: A61K31/198
- IPC: A61K31/198 ; A61K45/06 ; A61K31/45
Abstract:
The present invention relates to a neurodegenerative disease treatment use, which is a novel use of Ramalin, and, more specifically, to a composition for preventing or treating neurodegenerative diseases, containing Ramalin, which has an inflammasome and BACE1 expression inhibitory activity. Ramalin according to the present invention has an effect of improving a cognitive ability by inhibiting the expression of an inflammatory factor, which contains an NLRP inflammasome protein, and BACE1, and is thus useful for preventing or treating memory disorder and neurodegenerative diseases.
Public/Granted literature
- US20170304244A1 COMPOSITION FOR PREVENTING OR TREATING NEURODEGENERATIVE DISEASES, CONTAINING RAMALIN Public/Granted day:2017-10-26
Information query
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