A vehicle body frame includes a longitudinally extending roof side rail. The roof side rail includes an outer panel, an inner panel fixed to the outer panel to define a cavity therebetween, and a reinforcement panel disposed between and fixedly secured to the outer and inner panels. The reinforcement panel separates the cavity into an inner cavity and an outer cavity. The roof rail has a forward end portion and a rearward end portion. An acoustic spray foam control bulkhead is secured within the cavity at the rearward end portion of the roof side rail. The bulkhead includes a first sidewall and a second sidewall spaced from and opposed to the first sidewall. The first and second sidewalls are configured to at least partially confine within the inner cavity between the first and second sidewalls an acoustic spray foam injected into an injection inlet aperture provided on the inner panel.