- 专利标题： Inhibitors of HIF prolyl hydroxylase
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申请号： US15514536申请日： 2015-09-23
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公开(公告)号： US09969752B2公开(公告)日： 2018-05-15
- 发明人: Jiaqiang Cai , Alejandro Crespo , Xiaoxing Du , Byron Gabriel Dubois , Deodialsingh Guiadeen , Shankaran Kothandaraman , Ping Liu , Rongqiang Liu , Weiguo Quan , Christopher Sinz , Liping Wang
- 申请人： MERCK SHARP & DOHME CORP. , MSD R&D (CHINA) CO., LTD.
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 代理商 Matthew A. Leff; Gloria M. Fuentes
- 优先权： WOPCT/CN2014/087697 20140928
- 国际申请： PCT/US2015/051571 WO 20150923
- 国际公布： WO2016/049099 WO 20160331
- 主分类号： C07D471/06
- IPC分类号： C07D471/06 ; C07D498/06 ; C07D513/06 ; C07D498/16
摘要：
The present invention concerns compounds of formula I or pharmaceutically acceptable salts thereof, which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such as anemia and like conditions, as well as pharmaceutical compositions comprising such a compound and a pharmaceutical carrier.
公开/授权文献
- US20170233412A1 INHIBITORS OF HIF PROLYL HYDROXYLASE 公开/授权日：2017-08-17
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