专利检索 ap:("MERCK SHARP & DOHME CORP." OR "MSD R&D (CHINA) CO., LTD.") AND inv:"Byron Gabriel Dubois" 第 1 页

1.

发明授权
Inhibitors of HIF prolyl hydroxylase 有权

公开(公告)号：US09969752B2

公开(公告)日：2018-05-15

申请号：US15514536

申请日：2015-09-23

申请人： MERCK SHARP & DOHME CORP. , MSD R&D (CHINA) CO., LTD.

发明人： Jiaqiang Cai , Alejandro Crespo , Xiaoxing Du , Byron Gabriel Dubois , Deodialsingh Guiadeen , Shankaran Kothandaraman , Ping Liu , Rongqiang Liu , Weiguo Quan , Christopher Sinz , Liping Wang

IPC分类号： C07D471/06 , C07D498/06 , C07D513/06 , C07D498/16

CPC分类号： C07D513/06 , C07D471/04 , C07D471/06 , C07D498/04 , C07D498/06 , C07D498/16 , C07D513/04

摘要： The present invention concerns compounds of formula I or pharmaceutically acceptable salts thereof, which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such as anemia and like conditions, as well as pharmaceutical compositions comprising such a compound and a pharmaceutical carrier.