- 专利标题： Compositions of adenosine deaminase-2 (ADA2), variants thereof and methods of using same
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申请号： US15094908申请日： 2016-04-08
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公开(公告)号： US09969998B2公开(公告)日： 2018-05-15
- 发明人: Christopher D. Thanos , Lin Wang , H. Michael Shepard
- 申请人： Halozyme, Inc.
- 申请人地址： US CA San Diego
- 专利权人： Halozyme, Inc.
- 当前专利权人： Halozyme, Inc.
- 当前专利权人地址： US CA San Diego
- 代理机构： Dentons US LLP
- 代理商 Stephanie Seidman
- 主分类号： C12N9/78
- IPC分类号： C12N9/78 ; A61K38/48 ; A61K38/00
摘要：
Provided are variant adenosine deaminase 2 (ADA2) proteins, conjugates thereof and compositions containing the proteins and/or conjugates. Also provided are methods and uses of the ADA2 proteins or conjugates for treating diseases and conditions, such as a tumor or cancer, and in particular any disease or condition associated with elevated adenosine or other associated marker.
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