- 专利标题： Polymorphic forms and co-crystals of a c-Met inhibitor
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申请号： US15293511申请日： 2016-10-14
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公开(公告)号： US09981988B2公开(公告)日： 2018-05-29
- 发明人: David Bauer , Matthew Bio , Melanie Cooke , Katrina W. Copeland , Matthew Peterson , Michele Potashman , Roman Shimanovich , Helming Tan
- 申请人： AMGEN, INC.
- 申请人地址： US CA Thousand Oaks
- 专利权人： AMGEN INC.
- 当前专利权人： AMGEN INC.
- 当前专利权人地址： US CA Thousand Oaks
- 代理机构： Lucas & Mercanti, LLP
- 主分类号： C07D519/00
- IPC分类号： C07D519/00 ; A61K31/52 ; C07C55/10 ; C07C55/12 ; C07C57/10 ; C07C57/145 ; C07C275/02
摘要：
Provided herein are novel polymorphic forms and co-crystals of a compound useful in the treatment, prevention, or amelioration of cancer. In particular, the invention provides polymorphs and co-crystals of 6-{(1R)-1-[8-fluoro-6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)-one, which is an inhibitor of c-Met.
公开/授权文献
- US20170029443A1 POLYMORPHIC FORMS AND CO-CRYSTALS OF A C-MET INHIBITOR 公开/授权日：2017-02-02
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