- 专利标题: Compounds comprising self-immolative group
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申请号: US14898932申请日: 2015-05-27
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公开(公告)号: US09993568B2公开(公告)日: 2018-06-12
- 发明人: Yong Zu Kim , Tae Kyo Park , Sung Ho Woo , Sun Young Kim , Jong Un Cho , Doo Hwan Jung , Ji Young Min , Hyang Sook Lee , Yun Hee Park , Jeong Hee Ryu , Kyu Man Oh , Yeong Soo Oh , Jeiwook Chae , Ho Young Song , Chul-Woong Chung , Jeon Yang
- 申请人: LegoChem Biosciences, Inc.
- 申请人地址: KR Daejeon
- 专利权人: LegoChem Biosciences, Inc.
- 当前专利权人: LegoChem Biosciences, Inc.
- 当前专利权人地址: KR Daejeon
- 代理机构: Foley Hoag LLP
- 代理商 David P. Halstead; Lucas P. Watkins
- 优先权: KR10-2014-0064360 20140528; KR10-2015-0073161 20150526
- 国际申请: PCT/KR2015/005299 WO 20150527
- 国际公布: WO2015/182984 WO 20151203
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; C07K16/32 ; A61K47/48
摘要:
Provided are methods of use of compounds comprising a self-immolative group, which compounds may include a protein (for example, an oligopeptide, a polypeptide, an antibody, or the like) having substrate-specificity for a target and an active agent (for example, a drug, a toxin, a ligand, a detection probe, or the like) having a specific function or activity.
公开/授权文献
- US20170095576A1 COMPOUNDS COMPRISING SELF-IMMOLATIVE GROUP 公开/授权日:2017-04-06
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