Invention Grant
- Patent Title: PEG-Prom mediated surface expression of avidin/streptavidin
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Application No.: US14895125Application Date: 2014-06-04
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Publication No.: US09994865B2Publication Date: 2018-06-12
- Inventor: Paul B. Fisher , Swadesh K. Das , Mitchell E. Menezes , Devanand Sarkar , Martin G. Pomper
- Applicant: The Johns Hopkins University , Virginia Commonwealth University
- Applicant Address: US MD Baltimore US VA Richmond
- Assignee: The Johns Hopkins University,Virginia Commonwealth University
- Current Assignee: The Johns Hopkins University,Virginia Commonwealth University
- Current Assignee Address: US MD Baltimore US VA Richmond
- Agency: Foley & Lardner LLP
- International Application: PCT/US2014/040913 WO 20140604
- International Announcement: WO2014/197599 WO 20141211
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N15/85 ; C12N15/64 ; C07K14/47 ; G01N33/50 ; G01N33/574 ; A61K38/16 ; A61K38/17 ; A61K38/20 ; A61K41/00 ; A61K49/00 ; A61N7/00 ; C07K14/36 ; C07K14/465 ; C07K14/54 ; C12N7/00 ; C12N15/86 ; C12N15/62 ; B82Y5/00 ; B82Y15/00
Abstract:
The presently disclosed subject matter relates to compositions and methods directed to cancer theranostic nucleic acid constructs that permit simultaneous cancer-specific viral replication, expression of a diagnostic gene product, and expression of a therapeutic gene.
Public/Granted literature
- US20160108429A1 PEG-PROM MEDIATED SURFACE EXPRESSION OF AVIDIN/STREPTAVIDIN Public/Granted day:2016-04-21
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