再颁专利
USRE34705E Nucleotidic sequence coding the surface antigen of the hepatitis B
virus, vector containing said nucleotidic sequence, process allowing
the obtention thereof and antigen obtained thereby
失效
编码乙型肝炎病毒的表面抗原的核苷酸序列,含有所述核苷酸序列的载体,允许其获得的过程和由此获得的抗原
- 专利标题: Nucleotidic sequence coding the surface antigen of the hepatitis B virus, vector containing said nucleotidic sequence, process allowing the obtention thereof and antigen obtained thereby
- 专利标题(中): 编码乙型肝炎病毒的表面抗原的核苷酸序列,含有所述核苷酸序列的载体,允许其获得的过程和由此获得的抗原
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申请号: US640494申请日: 1991-01-14
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公开(公告)号: USRE34705E公开(公告)日: 1994-08-23
- 发明人: Francis Galibert , Pierre Tiollais , Patrick Charnay
- 申请人: Francis Galibert , Pierre Tiollais , Patrick Charnay
- 申请人地址: FRX Paris FRX Paris
- 专利权人: Institut Pasteur,Institut National de la Sante et de la Recherche Medicale
- 当前专利权人: Institut Pasteur,Institut National de la Sante et de la Recherche Medicale
- 当前专利权人地址: FRX Paris FRX Paris
- 优先权: FRX7921811 19790830; FRX8009039 19800422
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; C07K14/02 ; C07K7/06 ; A61K37/02 ; C07K13/00
摘要:
Nucleic acid of reduced size and vector containing said nucleotidic sequence of which DNA codes an immunogenic peptidic sequence capable of inducing the generation of antibodies to the virus of viral hepatitis B. It comprises totally or partly the sequence of nucleotides represented in FIG. 3A. Application to the production by cloning in a bacterium of an immunogenic protein immunizing against hepatitis B, or application to the obtention of probes for the diagnosis of the presence of Dane particles in a serum.
公开/授权文献
- US5829176A Card holder 公开/授权日:1998-11-03
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