再颁专利
- 专利标题: Carbapenem compounds, and compositions containing them
- 专利标题(中): 碳青霉烯化合物和含有它们的组合物
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申请号: US52849申请日: 1987-05-20
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公开(公告)号: USRE34960E公开(公告)日: 1995-05-30
- 发明人: Tetsuo Miyadera , Yukio Sugimura , Toshihiko Hashimoto , Teruo Tanaka , Kimio Iino , Tomoyuki Shibata , Shinichi Sugawara
- 申请人: Tetsuo Miyadera , Yukio Sugimura , Toshihiko Hashimoto , Teruo Tanaka , Kimio Iino , Tomoyuki Shibata , Shinichi Sugawara
- 申请人地址: JPX Tokyo
- 专利权人: Sankyo Company, Limited
- 当前专利权人: Sankyo Company, Limited
- 当前专利权人地址: JPX Tokyo
- 优先权: JPX56-129648 19810819; JPX57-81067 19820514
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; A61K31/40 ; C07D20060101 ; C07D207/12 ; C07D477/00 ; C07D477/20 ; C07D487/00 ; C07D487/06
摘要:
Compounds of formula (I): ##STR1## .[.[.]. wherein: R.sup.1 .[.represents a hydrogen atom, an alkyl group, an alkoxy group or various substituted alkyl groups.]. .Iadd.is hydroxyethyl; .Iaddend.R.sup.2 represents a group of formula ##STR2## in which ##STR3## .[.represents an alicyclic amine group having from 4 to 8 ring atoms, optionally having a single double bond, optionally containing an additional hetero-atom and optionally having an oxo group on the ring;.]. .Iadd.is a 3-pyrrolidinyl group; .Iaddend.X represents a hydrogen atom.[.; an alkyl group, an alkoxy group, an alkylthio group, an alkylsulphinyl group, an alkylsulphonyl group, a hydroxy group, a halogen atom or various substituted alkyl groups.].;Y represents .[.a hydrogen atom, an alkyl group, an aliphatic acyl group or an acylimidoyl.]. .Iadd.an acetylimidoyl .Iaddend.group; andR.sup.3 represents a carboxy group or a protected carboxy group.[.].].and pharmaceutically acceptable salts thereof have valuable antibacterial activity, especially in vivo.
公开/授权文献
- USD391777S Seat 公开/授权日:1998-03-10
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