再颁专利
- 专利标题: Substituted 3-cyanoquinolines
- 专利标题(中): 取代的3-氰基喹啉
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申请号: US12785269申请日: 2010-05-21
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公开(公告)号: USRE42376E1公开(公告)日: 2011-05-17
- 发明人: Allan Wissner , Hwei-Ru Tsou , Dan M. Berger , Middleton B. Floyd, Jr. , Philip R. Hamann , Nan Zhang , Philip Frost
- 申请人: Allan Wissner , Hwei-Ru Tsou , Dan M. Berger , Middleton B. Floyd, Jr. , Philip R. Hamann , Nan Zhang , Philip Frost
- 申请人地址: US NJ Madison
- 专利权人: Wyeth Holdings Corporation
- 当前专利权人: Wyeth Holdings Corporation
- 当前专利权人地址: US NJ Madison
- 代理商 Jeffrey H. Tidwell; Stephen D. Prodnuk; David Rubin
- 主分类号: A61K31/47
- IPC分类号: A61K31/47 ; C07D215/44
摘要:
This invention provides compounds of formula I having the structure wherein G1, G2, R1, R4, Z, n, and X are defined in the specification or a pharmaceutically acceptable salt thereof which are useful as antineoplastic agents and in the treatment of polycystic kidney disease.
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