- 专利标题: [1,2,4]triazolo[1,5-a]pyridinyl substituted indole compounds
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申请号: US17584147申请日: 2022-01-25
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公开(公告)号: USRE49931E1公开(公告)日: 2024-04-23
- 发明人: Alaric J. Dyckman , Dharmpal S. Dodd , Christopher P. Mussari , Laxman Pasunoori , Sreekantha Ratna Kumar
- 申请人: Bristol-Myers Squibb Company
- 申请人地址: US NJ Princeton
- 专利权人: Bristol-Myers Squibb Company
- 当前专利权人: Bristol-Myers Squibb Company
- 当前专利权人地址: US NJ Princeton
- 代理机构: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- 优先权: IN 1611022328 2016.06.29
- 主分类号: A61K31/4196
- IPC分类号: A61K31/4196 ; A61K31/437 ; A61K31/4427 ; A61K45/06 ; C07D249/00 ; C07D471/04
摘要:
Disclosed are compounds of Formula (I)
or a salt thereof, wherein R1, R2, R3, R4, R5, m, n, and p are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.
or a salt thereof, wherein R1, R2, R3, R4, R5, m, n, and p are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.
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