发明申请
WO1990006509A1 ISOLATION OF FETAL CELLS FROM MATERNAL BLOOD TO ENABLE PRENATAL DIAGNOSIS
审中-公开
从母体细胞中分离出阴道细胞以达到预期的诊断
- 专利标题: ISOLATION OF FETAL CELLS FROM MATERNAL BLOOD TO ENABLE PRENATAL DIAGNOSIS
- 专利标题(中): 从母体细胞中分离出阴道细胞以达到预期的诊断
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申请号: PCT/AU1989000517申请日: 1989-11-29
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公开(公告)号: WO1990006509A1公开(公告)日: 1990-06-14
- 发明人: THE FLINDERS UNIVERSITY OF SOUTH AUSTRALIA
- 申请人: THE FLINDERS UNIVERSITY OF SOUTH AUSTRALIA , MUELLER, Utz, Walter , HAWES, Catherine, Stezia
- 专利权人: THE FLINDERS UNIVERSITY OF SOUTH AUSTRALIA,MUELLER, Utz, Walter,HAWES, Catherine, Stezia
- 当前专利权人: THE FLINDERS UNIVERSITY OF SOUTH AUSTRALIA,MUELLER, Utz, Walter,HAWES, Catherine, Stezia
- 优先权: AUPJ 19881206
- 主分类号: G01N33/53
- IPC分类号: G01N33/53
摘要:
This invention relates to a method for the isolation of trophoblast (placental) cells from the blood of a pregnant mammal so as to provide the essential starting material, namely cells derived from the fetus, to enable genetic and/or biochemical information about the fetus to be obtained. In particular, this invention relates to the use of monoclonal antibodies specific for membrane protein markers on mammalian trophoblasts to isolate trophoblast cells from maternal blood. These cells may then be used to obtain fetal genetic and/or biochemical information early in pregnancy. The present invention is particularly relevant for detecting human fetal abnormalities.
IPC分类: