Invention Application
- Patent Title: CONTROLLED RELEASE AQUEOUS EMULSION
- Patent Title (中): 控制释放水乳液
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Application No.: PCT/US1995007908Application Date: 1995-06-21
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Publication No.: WO1995035096A1Publication Date: 1995-12-28
- Inventor: ASCENT PHARMACEUTICALS, INC. , TABIBI, S., Esmail , MENDES, Robert, W. , PATHAK, Nitin, P.
- Applicant: ASCENT PHARMACEUTICALS, INC.
- Assignee: ASCENT PHARMACEUTICALS, INC.
- Current Assignee: ASCENT PHARMACEUTICALS, INC.
- Priority: US8/263,277 19940621; US950619 19950619
- Main IPC: A61K09/14
- IPC: A61K09/14
Abstract:
A controlled release aqueous emulsion is disclosed, as are its method of manufacture and use as a vehicle for delivering medicaments in liquid form. A contemplated emulsion comprises a wax containing oil-in-water emulsion having an average oil particle size of about 100 nm to about 250 nm, a pH value of about 4.5 to about 8.0 and a viscosity at 20-25 C of 1 to about 1000 cps. The oil and water phases are emulsified by an emulsifying agent that provides freedom from phase separation at a pH value of about 4.5 to about 8, while also providing phase separation at a pH value below about 2.0.
Information query