Enzymatic oxidation system with enzymatic effect-enhancing compounds for use inter alia in the treatment of wood pulp waste waters in the paper industry and other industrial branches, in the production of lignin solutions or gels, corresponding binders/adhesives and wooden composite materials, and as enzymatic deinking system and color stripping system for used paper, oxidation system in organic synthesis and coal hydrogenation, containing: a) at least one oxidation catalyst, b) at least one oxidizing agent, c) at least one mediator selected from the group of the hydroxylamines, hydroylamine derivatives, hydroxamic acids, hydroxamic acid derivatives, of the aliphatic, cycloaliphatic, heterocyclic or aromatic compounds, containing at least on N-hydroxy, oxime, N-oxi or N,N'-dioxi function, and/or at least one mediator from the group of the amides such as hydrazides or 1,2,4-triazolidin-3,5-dione (urazoles) and/or at least one mediator from the group of the imides such as hydantoin and/or at least one mediator from the group of the oxocarbons. A mediation intensifier can also be used.