A method for producing solid, spherical materials containing at least one biologically active substance that is homogeneously dispersed in an auxiliary agent template by mixing said biologically active substance with one or several auxiliary agents in a melt, extruding and shaping said melt using a nozzle, characterized in that the melt containing the biologically active substance and auxiliary agents is discharged from the nozzle in the form of drops by exciting the nozzle with vibrations and the drops are frozen and solidified by coming into contact with a liquid.