发明申请
WO0179155A3 POLYCYCLIC ARYL AND HETEROARYL SUBSTITUTED 1,4-QUINONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE
审中-公开
用于选择性抑制凝聚剂CASCADE的多环芳烃和杂环取代的1,4-Quonones
- 专利标题： POLYCYCLIC ARYL AND HETEROARYL SUBSTITUTED 1,4-QUINONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE
- 专利标题（中）： 用于选择性抑制凝聚剂CASCADE的多环芳烃和杂环取代的1,4-Quonones
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申请号： PCT/US0111798申请日： 2001-04-10
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公开(公告)号： WO0179155A3公开(公告)日： 2002-05-16
- 发明人: SOUTH MICHAEL S , PARLOW JOHN J
- 申请人： PHARMACIA CORP , SOUTH MICHAEL S , PARLOW JOHN J
- 专利权人： PHARMACIA CORP,SOUTH MICHAEL S,PARLOW JOHN J
- 当前专利权人： PHARMACIA CORP,SOUTH MICHAEL S,PARLOW JOHN J
- 优先权： US19797500 2000-04-17; US25233300 2000-11-20
- 主分类号： A61P7/02
- IPC分类号： A61P7/02 ; A61K31/165 ; A61P9/00 ; A61P9/10 ; A61P11/00 ; A61P35/00 ; C07C257/18 ; C07D295/13 ; C07C237/18
摘要：
The invention relates to polycyclic aryl and heteroaryl substituted 1,4-quinone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.
