Invention Application
WO2003018605A2 SOLID-PHASE SYNTHESIS OF OLIGOSACCHARIDES AND GLYCOPEPTIDES USING GLYCOSYNTHASES
审中-公开
使用谷氨酰胺的寡糖和糖苷的固相合成
- Patent Title: SOLID-PHASE SYNTHESIS OF OLIGOSACCHARIDES AND GLYCOPEPTIDES USING GLYCOSYNTHASES
- Patent Title (中): 使用谷氨酰胺的寡糖和糖苷的固相合成
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Application No.: PCT/IB2002/003915Application Date: 2002-08-26
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Publication No.: WO2003018605A2Publication Date: 2003-03-06
- Inventor: WITHERS, Stephen, G. , JENSEN, Knud, J. , PETERSEN, Lars , TOLBERG, Jakob, L.
- Applicant: UNIVERSITY OF BRITISH COLUMBIA , WITHERS, Stephen, G. , JENSEN, Knud, J. , PETERSEN, Lars , TOLBERG, Jakob, L.
- Applicant Address: Industry Liaison Office, 2194 Health Sciences Mall, IRC Room 331, Vancouver, British Columbia V6T 1Z3 CA
- Assignee: UNIVERSITY OF BRITISH COLUMBIA,WITHERS, Stephen, G.,JENSEN, Knud, J.,PETERSEN, Lars,TOLBERG, Jakob, L.
- Current Assignee: UNIVERSITY OF BRITISH COLUMBIA,WITHERS, Stephen, G.,JENSEN, Knud, J.,PETERSEN, Lars,TOLBERG, Jakob, L.
- Current Assignee Address: Industry Liaison Office, 2194 Health Sciences Mall, IRC Room 331, Vancouver, British Columbia V6T 1Z3 CA
- Priority: US60/314,921 20010824
- Main IPC: C07K
- IPC: C07K
Abstract:
The present invention provides materials and methods for the solid-phase synthesis of oligosaccharides and glycopeptides. Such materials and methods include mutant glycosidase enzymes, or "glycosynthases", chemically-derivatized acceptor molecules, and specific solid support matrices.
Public/Granted literature
- WO2003018605A3 SOLID-PHASE SYNTHESIS OF OLIGOSACCHARIDES AND GLYCOPEPTIDES USING GLYCOSYNTHASES Public/Granted day:2003-03-06
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