Invention Application
WO2004038005A3 METHODS OF IDENTIFYING REDUCED INTERNALIZATION TRANSMEMBRANE RECEPTOR AGONISTS
审中-公开
鉴定减少内源性转录组受体激动剂的方法
- Patent Title: METHODS OF IDENTIFYING REDUCED INTERNALIZATION TRANSMEMBRANE RECEPTOR AGONISTS
- Patent Title (中): 鉴定减少内源性转录组受体激动剂的方法
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Application No.: PCT/US0333961Application Date: 2003-10-24
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Publication No.: WO2004038005A3Publication Date: 2005-02-03
- Inventor: LOOMIS CARSON R , OAKLEY ROBERT H , WANG SHUNTAI , ECKHARDT ALLEN E
- Applicant: NORAK BIOSCIENCES INC , LOOMIS CARSON R , OAKLEY ROBERT H , WANG SHUNTAI , ECKHARDT ALLEN E
- Assignee: NORAK BIOSCIENCES INC,LOOMIS CARSON R,OAKLEY ROBERT H,WANG SHUNTAI,ECKHARDT ALLEN E
- Current Assignee: NORAK BIOSCIENCES INC,LOOMIS CARSON R,OAKLEY ROBERT H,WANG SHUNTAI,ECKHARDT ALLEN E
- Priority: US42153802 2002-10-25
- Main IPC: C12N
- IPC: C12N20060101 ; G01N33/53 ; G01N33/566 ; G01N33/567
Abstract:
Described herein are methods of identifying a transmembrane receptor (TMR) agonist and compounds identified by this method. The TMR agonist (TMRA) is capable of activating TMR signaling while exhibiting reduced TMR internalization over a control compound.
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