Invention Application
WO2005016883A2 ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF
审中-公开
丙烯酰胺衍生物作为VLA-1 INTEGRIN ANTAGONISTS及其用途
- Patent Title: ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF
- Patent Title (中): 丙烯酰胺衍生物作为VLA-1 INTEGRIN ANTAGONISTS及其用途
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Application No.: PCT/US2004026653Application Date: 2004-08-12
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Publication No.: WO2005016883A2Publication Date: 2005-02-24
- Inventor: BOYD STEVEN A , MILLER SCOTT , THOMAS ALLEN , XU RUI , LEHUEROU YVAN , GUNAWARDANA INDRANI , ZHANG GAN , DEMEESE JASON , MCLAUGHLIN MARTIN , YANIK MATTHEW , LUPHER MARK L JR , JACOBSON IRINA C , THORSETT EUGENE D , FAROUZ FRANCINE S , KASAR RAMESH A
- Applicant: ICOS CORP , BOYD STEVEN A , MILLER SCOTT , THOMAS ALLEN , XU RUI , LEHUEROU YVAN , GUNAWARDANA INDRANI , ZHANG GAN , DEMEESE JASON , MCLAUGHLIN MARTIN , YANIK MATTHEW , LUPHER MARK L JR , JACOBSON IRINA C , THORSETT EUGENE D , FAROUZ FRANCINE S , KASAR RAMESH A
- Assignee: ICOS CORP,BOYD STEVEN A,MILLER SCOTT,THOMAS ALLEN,XU RUI,LEHUEROU YVAN,GUNAWARDANA INDRANI,ZHANG GAN,DEMEESE JASON,MCLAUGHLIN MARTIN,YANIK MATTHEW,LUPHER MARK L JR,JACOBSON IRINA C,THORSETT EUGENE D,FAROUZ FRANCINE S,KASAR RAMESH A
- Current Assignee: ICOS CORP,BOYD STEVEN A,MILLER SCOTT,THOMAS ALLEN,XU RUI,LEHUEROU YVAN,GUNAWARDANA INDRANI,ZHANG GAN,DEMEESE JASON,MCLAUGHLIN MARTIN,YANIK MATTHEW,LUPHER MARK L JR,JACOBSON IRINA C,THORSETT EUGENE D,FAROUZ FRANCINE S,KASAR RAMESH A
- Priority: US49560703 2003-08-14
- Main IPC: A61K31/397
- IPC: A61K31/397 ; A61K31/4178 ; A61K31/4535 ; A61K31/4709 ; A61K31/4725 ; A61K31/506 ; C07D205/04 ; C07D211/00 ; C07D211/58 ; C07D211/62 ; C07D401/06 ; C07D401/12 ; C07D403/12 ; C07D405/12 ; C07D409/06 ; C07D409/12 ; C07D409/14 ; C07D413/12 ; C07D413/14 ; C07D417/12
Abstract:
Compounds that are VLA-1 integrin antagonists are disclosed. Also disclosed are compositions containing such compounds, and methods of using such compounds in treating diseases mediated, at least in part, by the VLA-1 integrin.
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