Invention Application
- Patent Title: ARTIFICIAL IMMUNE SYSTEM: METHODS FOR MAKING AND USE
- Patent Title (中): 人工免疫系统：制造和使用的方法
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Application No.: PCT/US2005014444Application Date: 2005-04-28
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Publication No.: WO2005104755A3Publication Date: 2008-08-21
- Inventor: WARREN WILLIAM L , FAHLENKAMP HEATHER , HIGBEE RUSSELL , KACHURIN ANATOLY , LI CONAN K N , NGUYEN MIKE , PARKHILL ROBERT , SANCHEZ GUZMAN , IRVINE DARRELL J , RANDLOLPH GWENDALYN , NACOHEN NIR , TORBETT BRUCE
- Applicant: VAXDESIGN CORP , WARREN WILLIAM L , FAHLENKAMP HEATHER , HIGBEE RUSSELL , KACHURIN ANATOLY , LI CONAN K N , NGUYEN MIKE , PARKHILL ROBERT , SANCHEZ GUZMAN , IRVINE DARRELL J , RANDLOLPH GWENDALYN , NACOHEN NIR , TORBETT BRUCE
- Assignee: VAXDESIGN CORP,WARREN WILLIAM L,FAHLENKAMP HEATHER,HIGBEE RUSSELL,KACHURIN ANATOLY,LI CONAN K N,NGUYEN MIKE,PARKHILL ROBERT,SANCHEZ GUZMAN,IRVINE DARRELL J,RANDLOLPH GWENDALYN,NACOHEN NIR,TORBETT BRUCE
- Current Assignee: VAXDESIGN CORP,WARREN WILLIAM L,FAHLENKAMP HEATHER,HIGBEE RUSSELL,KACHURIN ANATOLY,LI CONAN K N,NGUYEN MIKE,PARKHILL ROBERT,SANCHEZ GUZMAN,IRVINE DARRELL J,RANDLOLPH GWENDALYN,NACOHEN NIR,TORBETT BRUCE
- Priority: US56584604 2004-04-28
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; A01N63/00 ; A61K35/26 ; C12N5/00 ; C12N5/071 ; G01N33/50
Abstract:
The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the normal tissues that interact with vaccines in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interaction with the immune system.
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