Invention Application
WO2006074330A3 INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME
审中-公开
11-羟基脱氢酶脱氢酶1型酶的抑制剂
- Patent Title: INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME
- Patent Title (中): 11-羟基脱氢酶脱氢酶1型酶的抑制剂
-
Application No.: PCT/US2006000402Application Date: 2006-01-05
-
Publication No.: WO2006074330A3Publication Date: 2007-01-25
- Inventor: ROHDE JEFFREY J , SHUAI QI , LINK JAMES T , PATEL JYOTI R , DINGES JURGEN , SORENSEN BRYAN K , YONG HONG , YEH VINCE S , KURUKULASURIYA RAVI
- Applicant: ABBOTT LAB , ROHDE JEFFREY J , SHUAI QI , LINK JAMES T , PATEL JYOTI R , DINGES JURGEN , SORENSEN BRYAN K , YONG HONG , YEH VINCE S , KURUKULASURIYA RAVI
- Assignee: ABBOTT LAB,ROHDE JEFFREY J,SHUAI QI,LINK JAMES T,PATEL JYOTI R,DINGES JURGEN,SORENSEN BRYAN K,YONG HONG,YEH VINCE S,KURUKULASURIYA RAVI
- Current Assignee: ABBOTT LAB,ROHDE JEFFREY J,SHUAI QI,LINK JAMES T,PATEL JYOTI R,DINGES JURGEN,SORENSEN BRYAN K,YONG HONG,YEH VINCE S,KURUKULASURIYA RAVI
- Priority: US64149605 2005-01-05; US32627706 2006-01-05
- Main IPC: C07C233/63
- IPC: C07C233/63 ; A61K31/165 ; A61K31/381 ; A61K31/415 ; A61K31/42 ; A61K31/4409 ; A61P3/04 ; A61P3/10 ; C07D213/56 ; C07D231/12 ; C07D261/08 ; C07D333/24
Abstract:
The present invention relates to compounds that are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action.
Information query
