Invention Application
WO2006105204A3 COMPOSITIONS AND THEIR USES DIRECTED TO THYMUS AND ACTIVATION-REGULATED CHEMOKINE (TARC)
审中-公开
组合物及其与三氯乙烯和激活性调节化学药物(TARC)的用途及其用途
- Patent Title: COMPOSITIONS AND THEIR USES DIRECTED TO THYMUS AND ACTIVATION-REGULATED CHEMOKINE (TARC)
- Patent Title (中): 组合物及其与三氯乙烯和激活性调节化学药物(TARC)的用途及其用途
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Application No.: PCT/US2006011478Application Date: 2006-03-28
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Publication No.: WO2006105204A3Publication Date: 2007-01-04
- Inventor: KARRAS JAMES G , DOBIE KENNETH W
- Applicant: ISIS PHARMACEUTICALS INC , KARRAS JAMES G , DOBIE KENNETH W
- Assignee: ISIS PHARMACEUTICALS INC,KARRAS JAMES G,DOBIE KENNETH W
- Current Assignee: ISIS PHARMACEUTICALS INC,KARRAS JAMES G,DOBIE KENNETH W
- Priority: US66625805 2005-03-28; US39089406 2006-03-27
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; A01N43/04 ; A61K31/07 ; C07H21/04
Abstract:
Disclosed herein are compounds, compositions and methods for modulating the expression of TARC in a cell, tissue or animal. Also provided are methods of target validation. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders related to expression of TARC, airway hyperresponsiveness, and/or pulmonary inflammation.
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