Invention Application
WO2007059065A2 DIAGNOSTIC METHOD FOR PROTEINACEOUS BINDING PAIRS, CARDIOVASCULAR CONDITIONS AND PREECLAMPSIA
审中-公开
蛋白质结合对，心血管病和前列腺疾病的诊断方法
- Patent Title: DIAGNOSTIC METHOD FOR PROTEINACEOUS BINDING PAIRS, CARDIOVASCULAR CONDITIONS AND PREECLAMPSIA
- Patent Title (中): 蛋白质结合对，心血管病和前列腺疾病的诊断方法
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Application No.: PCT/US2006/044059Application Date: 2006-11-14
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Publication No.: WO2007059065A2Publication Date: 2007-05-24
- Inventor: SOGIN, David, C. , LAIRD, Donald, M. , YU, Zhiguang , DOSS, Robert, C.
- Applicant: ABBOTT LABORATORIES , SOGIN, David, C. , LAIRD, Donald, M. , YU, Zhiguang , DOSS, Robert, C.
- Applicant Address: Dept. 377 Bldg AP6A-1, 100 Abbott Park Road, Abbott Park, Illinois 60064-6008 US
- Assignee: ABBOTT LABORATORIES,SOGIN, David, C.,LAIRD, Donald, M.,YU, Zhiguang,DOSS, Robert, C.
- Current Assignee: ABBOTT LABORATORIES,SOGIN, David, C.,LAIRD, Donald, M.,YU, Zhiguang,DOSS, Robert, C.
- Current Assignee Address: Dept. 377 Bldg AP6A-1, 100 Abbott Park Road, Abbott Park, Illinois 60064-6008 US
- Agency: BARTNICKI, Audrey, L. et al.
- Priority: US60/736,659 20051114; US11/367,126 20060303
- Main IPC: G01N33/566
- IPC: G01N33/566 ; G01N33/74 ; G01N33/53 ; G01N33/50
Abstract:
Method of measuring the quantity of a first proteinaceous specific binding partner (sbp) in a biological sample comprising detecting the binding of the first proteinaceous sbp with a labeled second proteinaceous sbp, wherein neither the first or second sbp is an antibody or fragment thereof, which is preferably a method of determining the amount of sFlt-1, particularly free sFlt-1, and the amount of PlGF, particularly free PlGF, in a sample, which is preferably used in a method of predicting risk of preeclampsia comprising comparing free PlGF to free sFlt-1.
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