Invention Application
WO2007107539A1 COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE
审中-公开
潜在的AMPA受体的化合物及其在医学中的应用
- Patent Title: COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE
- Patent Title (中): 潜在的AMPA受体的化合物及其在医学中的应用
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Application No.: PCT/EP2007/052568Application Date: 2007-03-19
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Publication No.: WO2007107539A1Publication Date: 2007-09-27
- Inventor: BRADLEY, Daniel, Marcus , CHAN, Wai, Ngor , HARRISON, Stephen , THATCHER, Robert , THEWLIS, Kevin, Michael , WARD, Simon, Edward
- Applicant: GLAXO GROUP LIMITED , BRADLEY, Daniel, Marcus , CHAN, Wai, Ngor , HARRISON, Stephen , THATCHER, Robert , THEWLIS, Kevin, Michael , WARD, Simon, Edward
- Applicant Address: Glaxo Wellcome House, Berkeley Avenue, Greenford Middlesex UB6 0NN GB
- Assignee: GLAXO GROUP LIMITED,BRADLEY, Daniel, Marcus,CHAN, Wai, Ngor,HARRISON, Stephen,THATCHER, Robert,THEWLIS, Kevin, Michael,WARD, Simon, Edward
- Current Assignee: GLAXO GROUP LIMITED,BRADLEY, Daniel, Marcus,CHAN, Wai, Ngor,HARRISON, Stephen,THATCHER, Robert,THEWLIS, Kevin, Michael,WARD, Simon, Edward
- Current Assignee Address: Glaxo Wellcome House, Berkeley Avenue, Greenford Middlesex UB6 0NN GB
- Agency: KONDO, Rie et al.
- Priority: GB0605589.1 20060320; GB0621438.1 20061027
- Main IPC: C07D231/56
- IPC: C07D231/56 ; C07D401/10 ; C07D403/10 ; C07D403/12 ; C07D405/12 ; C07D409/12 ; C07D413/10 ; C07D417/10 ; A61K31/416 ; A61P25/00
Abstract:
Compounds of formula (I) and salts and solvates are provided: formula (I). Processes for preparation, pharmaceutical compositions, and uses thereof as a medicament, for example in the treatment of a disease or condition mediated by a reduction or imbalance in glutamate receptor function, such as schizophrenia or cognition impairment, are also disclosed.
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