Invention Application
- Patent Title: MUTANT DNA POLYMERASES AND THEIR GENES FROM THERMOCOCCUS
- Patent Title (中): 突变DNA聚合酶及其基因
-
Application No.: PCT/KR2007/004827Application Date: 2007-10-02
-
Publication No.: WO2008066245A1Publication Date: 2008-06-05
- Inventor: LEE, Jung Hyun , KANG, Sung Gyun , KIM, Sang Jin , KWON, Kae Kyoung , LEE, Hyun Sook , KIM, Yun Jae , RYU, Yong Gu , BAE, Seung Seob , LIM, Jae Kyu , JEON, Jung Ho , CHO, Yo Na , JEONG, Insoon , KWON, Suk Tae , CHA, Sun Shin
- Applicant: KOREA OCEAN RESEARCH & DEVELOPMENT INSTITUTE , LEE, Jung Hyun , KANG, Sung Gyun , KIM, Sang Jin , KWON, Kae Kyoung , LEE, Hyun Sook , KIM, Yun Jae , RYU, Yong Gu , BAE, Seung Seob , LIM, Jae Kyu , JEON, Jung Ho , CHO, Yo Na , JEONG, Insoon , KWON, Suk Tae , CHA, Sun Shin
- Applicant Address: #1270 Sa 2-dong Sangnok-gu, Ansan Si Gyeonggi-do 426-744 KR
- Assignee: KOREA OCEAN RESEARCH & DEVELOPMENT INSTITUTE,LEE, Jung Hyun,KANG, Sung Gyun,KIM, Sang Jin,KWON, Kae Kyoung,LEE, Hyun Sook,KIM, Yun Jae,RYU, Yong Gu,BAE, Seung Seob,LIM, Jae Kyu,JEON, Jung Ho,CHO, Yo Na,JEONG, Insoon,KWON, Suk Tae,CHA, Sun Shin
- Current Assignee: KOREA OCEAN RESEARCH & DEVELOPMENT INSTITUTE,LEE, Jung Hyun,KANG, Sung Gyun,KIM, Sang Jin,KWON, Kae Kyoung,LEE, Hyun Sook,KIM, Yun Jae,RYU, Yong Gu,BAE, Seung Seob,LIM, Jae Kyu,JEON, Jung Ho,CHO, Yo Na,JEONG, Insoon,KWON, Suk Tae,CHA, Sun Shin
- Current Assignee Address: #1270 Sa 2-dong Sangnok-gu, Ansan Si Gyeonggi-do 426-744 KR
- Agency: YOON, Yuh-Gang
- Priority: KR10-2006-0119612 20061130
- Main IPC: C12N9/12
- IPC: C12N9/12
Abstract:
The present invention relates to mutant DNA polymerases and their genes isolated from Thermococcus sp. More specifically, the present invention relates to mutant DNA polymerases which are originally isolated from Thermococcus sp NAl. strain and produced by site-specific mutagenesis, their amino acid sequences, genes encoding said mutant DNA polymerases, their nucleic acids sequences, recombinant vectors containing said nucleic acids sequences, host cells transformed with thereof and methods for producing mutant DNA polymerase protein by using thereof. As mutant DNA polymerases according to the present invention have increased processivity by site-specific mutagenesis on exonuclease active site compared to wild type DNA polymerase, the present invention is broadly applicable for PCR in various molecular genetic technologies.
Information query
