Invention Application
- Patent Title: NAPHTHYRIDINE, DERIVATIVES AS P13 KINASE INHIBITORS
- Patent Title (中): 萘啶，衍生物作为P13激酶抑制剂
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Application No.: PCT/US2008/065021Application Date: 2008-05-29
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Publication No.: WO2008150827A1Publication Date: 2008-12-11
- Inventor: ADAMS, Nicholas, D. , BURGESS, Joelle, L. , CHAUDHARI, Amita, M. , KNIGHT, Steven, David , PARRISH, Cynthia, A.
- Applicant: SMITHKLINE BEECHAM CORPORATION , ADAMS, Nicholas, D. , BURGESS, Joelle, L. , CHAUDHARI, Amita, M. , KNIGHT, Steven, David , PARRISH, Cynthia, A.
- Applicant Address: One Franklin Plaza, P.O. Box 7929 Philadelphia, PA 19101 US
- Assignee: SMITHKLINE BEECHAM CORPORATION,ADAMS, Nicholas, D.,BURGESS, Joelle, L.,CHAUDHARI, Amita, M.,KNIGHT, Steven, David,PARRISH, Cynthia, A.
- Current Assignee: SMITHKLINE BEECHAM CORPORATION,ADAMS, Nicholas, D.,BURGESS, Joelle, L.,CHAUDHARI, Amita, M.,KNIGHT, Steven, David,PARRISH, Cynthia, A.
- Current Assignee Address: One Franklin Plaza, P.O. Box 7929 Philadelphia, PA 19101 US
- Agency: PENG, Tony, W. et al.
- Priority: US60/940,501 20070529
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A61K31/44
Abstract:
Invented is a method of inhibiting the activity/function of PB kinases using naphthyridine derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of naphthyridine derivatives.
Information query
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