Invention Application
- Patent Title: PROCESS FOR PRODUCING ORGANIC ACIDS BY CONTINUOUS FERMENTATION
- Patent Title (中): 连续发酵生产有机酸的方法
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Application No.: PCT/EE2008/000018Application Date: 2008-07-09
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Publication No.: WO2009006909A1Publication Date: 2009-01-15
- Inventor: ILUSHKA, Igor Valerianovich , RAKITIN, Vladimir Yuriyvich , SHVETS, Valeriy Fedorovich , KOZLOVSKIY, Roman Anatolievich , SUCHKOV, Yuri Pavlovich , KOLBAROV, Vambola Vijacheslavovich
- Applicant: NORDBIOCHEM OÜ , ILUSHKA, Igor Valerianovich , RAKITIN, Vladimir Yuriyvich , SHVETS, Valeriy Fedorovich , KOZLOVSKIY, Roman Anatolievich , SUCHKOV, Yuri Pavlovich , KOLBAROV, Vambola Vijacheslavovich
- Applicant Address: Kuuse 2 EE-63303 Polva EE
- Assignee: NORDBIOCHEM OÜ,ILUSHKA, Igor Valerianovich,RAKITIN, Vladimir Yuriyvich,SHVETS, Valeriy Fedorovich,KOZLOVSKIY, Roman Anatolievich,SUCHKOV, Yuri Pavlovich,KOLBAROV, Vambola Vijacheslavovich
- Current Assignee: NORDBIOCHEM OÜ,ILUSHKA, Igor Valerianovich,RAKITIN, Vladimir Yuriyvich,SHVETS, Valeriy Fedorovich,KOZLOVSKIY, Roman Anatolievich,SUCHKOV, Yuri Pavlovich,KOLBAROV, Vambola Vijacheslavovich
- Current Assignee Address: Kuuse 2 EE-63303 Polva EE
- Agency: SARAP, Margus
- Priority: EEP200700037 20070710
- Main IPC: C12P7/48
- IPC: C12P7/48 ; C12P7/54 ; C12P7/56
Abstract:
According to present invention, the lactic acid and other organic acids can be produced in a simple and inexpensive manner, so as to eliminate the disadvantages of the prior processes discussed above. It has been surprisingly found, that if to create such conditions at which growth rate of cells is minimal but sufficient for replacement cells death, in this case decrease of the specific consumption of carbohydrates per unit of lactate is take place. The growth rate of cells can be reduced by increase of temperature and decrease of pH up to critical and supercritical values for each microorganism and as well by decrease of amounts nutrients fed into the fermentor and by use of additives bacteriostatics. Preferably, the optimal growth rate of cells reach by combination of temperature, pH, by amount of used nutrients and bacteriostatics fed into the fermentor.
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