Invention Application
- Patent Title: NEW BIARYL DERIVATIVES
- Patent Title (中): 新的BIARYL衍生物
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Application No.: PCT/EP2008/062599Application Date: 2008-09-22
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Publication No.: WO2009043747A2Publication Date: 2009-04-09
- Inventor: AEBI, Johannes , BINGGELI, Alfred , GREEN, Luke , HARTMANN, Guido , MAERKI, Hans P. , MATTEI, Patrizio , RICKLIN, Fabienne , ROCHE, Olivier
- Applicant: F. HOFFMANN-LA ROCHE AG , AEBI, Johannes , BINGGELI, Alfred , GREEN, Luke , HARTMANN, Guido , MAERKI, Hans P. , MATTEI, Patrizio , RICKLIN, Fabienne , ROCHE, Olivier
- Applicant Address: Grenzacherstrasse 124 CH-4070 Basel CH
- Assignee: F. HOFFMANN-LA ROCHE AG,AEBI, Johannes,BINGGELI, Alfred,GREEN, Luke,HARTMANN, Guido,MAERKI, Hans P.,MATTEI, Patrizio,RICKLIN, Fabienne,ROCHE, Olivier
- Current Assignee: F. HOFFMANN-LA ROCHE AG,AEBI, Johannes,BINGGELI, Alfred,GREEN, Luke,HARTMANN, Guido,MAERKI, Hans P.,MATTEI, Patrizio,RICKLIN, Fabienne,ROCHE, Olivier
- Current Assignee Address: Grenzacherstrasse 124 CH-4070 Basel CH
- Agency: NIIZUMA, Yo
- Priority: EP07117656.4 20071001
- Main IPC: C07D401/04
- IPC: C07D401/04 ; C07D401/14 ; C07D403/14 ; C07D211/58 ; C07D243/08 ; A61K31/551 ; A61K31/454 ; A61K31/4545 ; A61K31/506 ; A61P9/00 ; A61P29/00 ; C07D413/14 ; C07D403/06
Abstract:
The invention is concerned with novel biaryl derivatives of Formula (I), wherein Formula (A), m, R 1 , R 2 , R 3 , X 1 , X 2 and X 3 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds are antagonists of CCR-2 receptor, CCR-5 receptor and/or CCR-3 receptor and can be used as medicaments.
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